To anyone struggling with depression, I chronic fatigue, anxiety & brain fog: you're not alone, you're not
"crazy" or a hypochondriac. You're not broken. Healing is so deeply possible and something I see on a daily basis. The area of clinical research known as "the cytokine model of cognitive function" looks at how brain inflammation is associated with cases of depression, anxiety, brain fog and autoimmune brain problems. This is something I have seen daily for the past 13+ years with new telehealth patient labs who are struggling with these nervous system dysregulation issues.
Inflammation decreases the firing rate of neurons in the frontal lobe of the brain in people with nervous system dysregulation. In cases of neuro-inflammation, medications like antidepressants are often not effective (or at best, "take the edge off" because they can act as a mild anti inflammatory) because they aren't addressing the underlying brain inflammation.
In short, if you sutter from depression, anxiety, brain tog or an autoimmune brain problem, blood-brain barrier permeability (or "leaky brain syndrome") neuro-inflammation and a comprehensive look at what factors are driving that inflammation (such as environmental toxins, bio-toxins like mold, an unhealthy gut, nutrient deficiencies and unresolved emotional trauma).